The TARGET BP OFF-MED Study is evaluating the Peregrine Procedure, a minimally invasive intervention that has been shown in early studies(6,7) to reduce blood pressure by deactivating problematic nerves surrounding the renal (kidney) artery that, through over-signaling, can contribute to high blood pressure.   


The Peregrine Procedure is a quick minimally invasive one-time procedure that is performed under local anesthesia. The Peregrine Catheter will be advanced through a small incision in your leg and guided up to the renal artery using angiography (like an X-ray). The system will deliver a small dose of dehydrated alcohol to the region just outside the artery where the sympathetic nerves are located, to deactivate the over-signalling of these nerves.